Weight Loss Drugs Can Boost Testosterone In Men With Obesity Or Diabetes

3 days ago

Anti-obesity medications tin importantly raise testosterone levels and amended wellness outcomes for men pinch obesity aliases type 2 diabetes, according to a caller study being presented Monday astatine ENDO 2025, nan Endocrine Society's yearly gathering successful San Francisco, Calif.

Testosterone not only plays a captious domiciled successful nan assemblage erstwhile it comes to antheral intersexual functioning, but it tin besides person an effect connected an individual's bony mass, fat distribution, musculus mass, spot and reddish humor compartment production. Increases successful assemblage weight and prevalence of type 2 glucosuria are often associated pinch lowered testosterone levels, resulting successful fatigue, decreased libido and value of life.

While it is good known that weight nonaccomplishment from manner changes aliases bariatric room increases testosterone levels, nan effect that anti-obesity medications whitethorn besides person connected these levels has not been wide studied. Our study is among nan first to supply compelling grounds that debased testosterone tin beryllium reversed pinch nan usage of commonly prescribed anti-obesity medications."

Shellsea Portillo Canales, M.D., endocrinology chap astatine SSM Health St. Louis University Hospital successful St. Louis, Mo.

To trial this hypothesis, researchers analyzed nan physics wellness records of 110 big men pinch obesity aliases type 2 glucosuria being treated pinch nan weight-loss medications semaglutide, dulaglutide aliases tirzepatide and who were not connected testosterone aliases hormonal therapy. Participants' full and free testosterone levels were measured earlier and during curen complete nan people of 18 months.

Along pinch 10% weight loss, nan proportionality of men pinch normal levels of some full and free testosterone roseate from 53% to 77%. These findings bespeak that anti-obesity medications besides tin person a affirmative effect connected nan reproductive wellness of men pinch obesity aliases type 2 diabetes.

"Results from this study show that location is simply a nonstop relationship betwixt nan usage of anti-obesity medications and testosterone levels," said Portillo Canales. "Doctors and their patients tin now see this people of medications not only for nan curen of obesity and to power humor sugar, but besides to use men's reproductive health."

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