A caller longitudinal study shows that rising ultra-processed nutrient intake successful young adults pinch a history of overweight aliases obesity sharply increases prediabetes risk. This shows really mundane eating habits whitethorn softly push glucose regularisation toward vulnerable territory.
Study: Ultra-processed nutrient intake is associated pinch altered glucose homeostasis successful young adults pinch a history of overweight aliases obesity: a longitudinal study. Image credit: Al More/Shutterstock.com
A caller study published successful nan diary Nutrition and Metabolism finds that ultra-processed nutrient intake whitethorn summation prediabetes and consequence factors associated pinch later development of type 2 diabetes successful young adults pinch a history of overweight aliases obesity.
The emergence of ultra-processed diets
Prediabetes has go a important nationalist wellness interest among young adults, arsenic this objective information tin summation nan consequence of early-onset type 2 diabetes. Type 2 glucosuria is simply a known consequence facet for galore chronic diseases and premature mortality. In nan U.S, its incidence is estimated to beryllium 17.9 per 100,000 young individuals.
Obesity is simply a awesome consequence facet for prediabetes and type 2 diabetes. Unhealthy manner factors, including an unhealthy fare and beingness inactivity, are considered awesome modifiable consequence factors for each these metabolic diseases.
Ultra-processed foods, including soft drinks, packaged snacks, margarine, and sausages, are calorie-dense nutrient items that incorporate precocious amounts of salt, sugar, and unhealthy fats, arsenic good arsenic debased amounts of dietary fiber and basal nutrients.
In nan U.S, much than half of nan full dietary power intake is composed of ultra-processed foods, which are known to summation nan consequence of cardiometabolic diseases. Many studies person linked ultra-processed nutrient intake pinch obesity and glucosuria consequence among adults. However, only a fewer studies person investigated nan wellness effects of ultra-processed foods successful children and adolescents, producing mixed results.
Given nan imaginable nexus betwixt prediabetes, type 2 diabetes, and obesity, and nan beingness of shared consequence factors, University of Southern California researchers, together pinch their collaborators, assessed whether ultra-processed nutrient intake increases nan consequence of glucosuria successful young adults pinch a history of overweight aliases obesity.
Measuring fare and metabolism
The study included a full of 85 young adults aged 17 to 22 years who had a history of overweight aliases obesity successful their adolescence. The participants, who had antecedently participated successful nan Children’s Health Study successful Southern California, were enrolled betwixt 2014 and 2018 and returned for a 2nd sojourn betwixt 2020 and 2022 (follow-up visit).
They completed 2 24-hour dietary recalls for dietary appraisal and estimation of ultra-processed nutrient intake.
Glucose homeostasis of participants was assessed done glucose tolerance test, glycated hemoglobin (a measurement of glycemic control) level, and insulin resistance.
How UPFs affected health
The study study revealed that a 10-percentage constituent summation successful ultra-processed nutrient intake complete a play of 4 years is associated pinch a 51 % higher consequence of processing prediabetes and a 158 % higher consequence of impaired glucose tolerance successful young adults pinch a history of overweight aliases obesity.
The summation successful ultra-processed nutrient intake betwixt baseline and follow-up visits was associated pinch a important emergence successful insulin guidance and a positive, albeit non-significant, relationship pinch higher assemblage wide scale (BMI), assemblage fat percentage, and fat mass.
Implications for young adults
The study highlights nan adverse effect of ultra-processed nutrient intake connected nan improvement of prediabetes and connected metabolic consequence factors that whitethorn lend to early type-2 diabetes, among young adults pinch a history of overweight aliases obesity.
The study focuses connected younker populations that person precocious reached a physically mature shape and are much apt to acquisition important manner changes that tin perchance lend to metabolic disorders. The study findings, therefore, person important nationalist wellness relevance.
Insulin guidance and pancreatic beta-cell dysfunction are 2 awesome hallmarks of type 2 diabetes. This study finds a important relation betwixt higher ultra-processed nutrient intake and accrued insulin resistance, highlighting a imaginable system done which unhealthy diets tin power nan early physiological changes associated pinch type 2 diabetes.
The study finds a positive, though non-significant, relation betwixt higher intake of ultra-processed foods and obesity-related assemblage creation measurements, suggesting that reducing intake of these unhealthy foods tin beryllium beneficial for some glucosuria and weight management.
Ultra-processed foods incorporate precocious amounts of salt, sugar, and saturated aliases trans fat, which tin importantly summation nan consequence of metabolic diseases. Existing grounds indicates that each these nutrient components are associated pinch nan improvement of obesity and glucosuria successful adults. Studies conducted connected children and adolescents bespeak that limiting added sweetener intake tin trim nan consequence of various chronic diseases.
All these findings, together pinch nan existent study findings, propose that nutrient components commonly recovered successful ultra-processed foods tin lend to overweight aliases obesity, which successful move tin perchance summation nan consequence of type 2 diabetes. These nutrient components tin beryllium considered arsenic applicable targets for nationalist wellness interventions.
Due to nan mini sample size, nan study lacks capable statistical powerfulness to observe associations betwixt ultra-processed nutrient intake and circumstantial important outcomes. Further large-scale studies are needed to ascertain whether these foods straight impact pancreatic beta-cell functions.
Furthermore, nan study involves young adults pinch a history of overweight aliases obesity successful their adolescence, which whitethorn restrict nan generalizability of its findings to different populations.
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Journal reference:
- Li Y. (2025). Ultra-processed nutrient intake is associated pinch altered glucose homeostasis successful young adults pinch a history of overweight aliases obesity: a longitudinal study. Nutrition and Metabolism. doi: https://doi.org/10.1186/s12986-025-01036-6. https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-025-01036-6
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