Substance Use Disorders Increase Risk Of Unplanned Hospital Readmissions

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People pinch immoderate type of constituent usage upset (SUD) guidelines a 24% higher consequence of having an unplanned infirmary readmission wrong 30 days of a erstwhile discharge compared pinch those without nan disorder, caller UCLA-led investigation finds.

People pinch opioid usage upset had nan highest 30-day readmission rates, astatine astir 40%, nan researchers found. Overall, group pinch SUDs comprise a disproportionate stock of patients pinch aggregate unplanned readmissions.

The higher consequence was existent only for group pinch constituent usage disorders who were discharged to homes without having been provided pinch post-acute care, said study co-author Steven Shoptaw, head of nan Center for Behavioral and Addiction Medicine astatine UCLA. The findings place a heretofore overlooked group pinch unsocial needs some during and aft discharge, he said.

Identifying a constituent usage upset successful nan aesculapian grounds apt identifies patients who look problems pinch taking bully attraction of themselves station discharge if location are fewer aliases nary supports astatine home. Barriers to taking bully attraction could see unmet societal needs specified arsenic safe and affordable housing, patient food, and employment. This tin complicate tasks associated pinch post-discharge rehabilitation, including attending follow-up appointments, filling prescriptions astatine nan pharmacy, and adhering to medications."

Steven Shoptaw, Director, Center for Behavioral and Addiction Medicine, UCLA

The findings will beryllium published July 23 successful nan peer-reviewed diary Addiction.

Unplanned infirmary readmissions are known to beryllium costly and person a antagonistic effect connected patients, specified arsenic expanding financial burdens, heightening nan consequence for hospital-acquired infections, and raising nan likelihood of falls.

The researchers examined information from astir 22,100 patients first admitted to 2 municipality world aesculapian centers successful 2022. They defined SUDs arsenic diagnoses pinch 1 aliases much of nan following: intoxicant related disorders (AUD); opioid related disorders (OUD); sedative, hypnotic aliases anxiolytic related disorders; cocaine related disorders; different stimulant related disorders, and different psychoactive constituent related disorders. They besides utilized immoderate different imaginable markers of SUDs specified arsenic alcoholic polyneuropathy, cardiomyopathy and fatty liver.

They recovered that 7.4% of nan patients had astatine slightest 1 constituent usage upset astatine first admission, including 4% pinch AUD and 2.4% had OUD, pinch nan remainder dispersed complete nan different disorders. About 9.7% of patients pinch immoderate of nan diagnosed SUDs, 9.3% pinch AUD and 11% pinch OUD were re-admitted wrong nan 30-day window.

While erstwhile studies person specifically linked AUD to 30-day unplanned readmission, nan researchers did not find an relation successful this study. They fishy this null uncovering could beryllium explained by a operation of diagnostic procedures successful inpatient settings arsenic good arsenic AUD severity, lodging status, income and employment-covariates that they did not examine. They were amazed by nan peculiarly precocious consequence of 30-day unplanned readmission for patients pinch OUD, who were apt being treated for co-morbidities related to opioid usage specified arsenic non-fatal overdoses and diseases specified arsenic endocarditis, cellulitis and osteomyelitis, arsenic these hospitals did not person general inpatient curen units for superior OUD.

SUDs are not ever detected successful hospitalized patients, peculiarly erstwhile they are not nan superior logic for nan patient's hospitalization, which whitethorn person led to misclassification of SUDs, nan researchers write. Other factors that whitethorn limit nan findings see nan anticipation that not each readmissions were captured because immoderate patients whitethorn person sought attraction astatine different hospitals not included successful nan study. The researchers besides did not seizure post-discharge mortality aliases unmeasured factors specified arsenic lodging position aliases magnitude of stay, and nan findings whitethorn not beryllium generalizable to different hospitals.

But nan findings tin constituent nan measurement to improving attraction for patients pinch constituent usage disorders, said Allison Rosen, investigation epidemiologist astatine UCLA and nan study's lead author.

"Implementing evidence-based practices for treating constituent usage disorders, specified arsenic starting patients connected medicine and/or behavioral therapy during their hospitalization and linking them to outpatient curen astatine discharge, could person nan imaginable to amended value of attraction for patients pinch constituent usage disorders, arsenic good arsenic reducing costs related to 30-day unplanned readmissions," Rosen said.

Dr. Sae Takada, Dr. Catherine Juillard, Dr. Yulsi Fernandez Montero, Dr. Amy Richards, and Steven Shoptaw of UCLA; Dr. Michelle Bholat of UC Riverside, and Serge Ngekeng of nan University of Buea successful Cameroon were co-authors connected nan study.

The UCLA Department of Family Medicine funded nan study.

Source:

Journal reference:

Rosen, A. D., et al. (2025) Unpacking nan nexus betwixt constituent usage disorders and 30-day unplanned readmission. Addiction. doi.org/10.1111/add.70136.

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