Results from nan Female Asian Nonsmoker Screening Study (FANSS) item nan imaginable worth of low-dose CT (LDCT) screening for lung crab among a increasing but underserved population: Asian women pinch nary history of smoking.
The study results were reported coming astatine nan International Association for nan Study of Lung Cancer 2025 World Conference connected Lung Cancer (WCLC).
FANSS is nan first known lung crab screening programme successful nan U.S. dedicated exclusively to a non-smoking population. The study screened 1000 eligible Asian women ages 40–74 utilizing LDCT and assessed lung crab discovery rates based connected Lung-RADS classifications.
Asian American women who person ne'er smoked person been recovered to beryllium doubly arsenic apt to create lung crab arsenic achromatic women successful nan aforesaid smoking category, according to antecedently reported research.
Our findings show a lung crab discovery complaint of 1.3%, which is higher than that reported successful nan National Lung Screening Trial (NLST) for high-risk smokers. These results support nan request to reconsider screening guidelines to see never-smoking high-risk groups."
Dr. Elaine Shum, from NYU Perlmutter Cancer Center
Dr. Shum and her squad reported respective important results:
- Lung-RADS distribution: 0 (2.2%), 1 (38.8%), 2 (52.1%), 3 (4.1%), and 4 (2.8%).
- Thirteen participants (1.3%) were diagnosed pinch invasive lung adenocarcinoma.
- Cancer stages astatine diagnosis: 9 Stage IA, 2 Stage IIB, and 2 Stage IIIB/C.
- All patients underwent surgical resection; nary lung crab deaths reported to date.
- Additional 14 patients pinch Lung-RADS 3 aliases 4 are nether further evaluation.
Dr. Shum reported that FANSS builds upon anterior activity specified arsenic nan TALENT study successful Taiwan and suggests that existent U.S. screening guidelines-which are constricted to individuals pinch a smoking history-may place high-risk nonsmoking populations.
"With continued follow-up and pending biomarker analysis, FANSS whitethorn supply nan information needed to grow evidence-based screening recommendations for non-smoking populations," she said.