Study: Formal Education Does Not Slow Brain Aging Or Cognitive Decline

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An world study published successful nan diary Nature Medicine casts uncertainty connected nan wide belief that higher levels of general acquisition straight protect against cognitive diminution and encephalon aging. The study analyzed longitudinal information from much than 170,000 group successful 33 occidental countries, making it 1 of nan largest studies of cognitive aging to date. The University of Barcelona and nan Institut Guttmann are nan only 2 centres successful Spain to participate successful nan study, led by nan University of Oslo (Norway) arsenic portion of nan European Lifebrain consortium.

The results reenforce nan request for policies and programmes to beforehand encephalon wellness that spell beyond cognitive activity and span nan full life course, not conscionable successful puerility and youth.

According to erstwhile studies, though nan full number of group pinch dementia worldwide is expanding owed to organization maturation and aging, nan incidence appears to beryllium decreasing and older adults person amended cognitive usability coming than they did 20 years ago. This inclination is attributed to manner changes successful nan population, and until now, nan astir wide held presumption held that general acquisition whitethorn supply protection against neurodegeneration aliases normal encephalon aging.

However, nan squad has recovered that though group pinch much years of general acquisition thin to commencement pinch a higher cognitive level successful adulthood, they do not acquisition slower cognitive diminution pinch age.

Arguably, having a higher level of acquisition puts you successful an advantageous position astatine nan opening of nan race, but erstwhile nan title starts it does not let you to spell faster and does not bespeak immoderate shortcuts: you will look nan aforesaid obstacles arsenic everyone else, and they will impact you conscionable for illustration everyone else."

Professor David Bartrés-Faz, from nan Faculty of Medicine and Health Sciences and nan UB Institute of Neurosciences (UBneuro), and main interrogator of nan Institut Guttman's Barcelona Brain Health Initiative (BBHI)

Previous studies person had conflicting results and were often constricted to mini aliases single-country samples. The now published study has analysed much than 420,000 neuropsychological tests and imaging tests of individuals from aggregate countries and cohorts (European, American, Asian and Australian) pinch different methodologies, making it 1 of nan astir robust and generalizable investigations connected nan subject. In total, 170,795 group aged complete 50 participated, belonging to 27 longitudinal cohorts and pinch a follow-up of up to 28 years per participant.

​​​​​Specifically, nan BBHI cohort contributed 966 subjects to nan study, while UB contributed 161. Participants underwent tests of memory, reasoning, processing velocity and language, and 6,472 individuals besides underwent encephalon MRI scans to analyse parameters specified arsenic full encephalon measurement and nan measurement of cardinal representation regions (hippocampus and prefrontal cortex).

A very akin evolution

According to nan results, a higher level of acquisition is associated pinch amended memory, larger intracranial measurement and a somewhat larger measurement of memory-sensitive encephalon regions. "One plausible mentation is that it is nan first neurobiological traits of individuals that favour higher acquisition attainment, and not nan different measurement around", notes interrogator Gabriele Cattaneo (BBHI). And each groups, sloppy of their level of education, showed a cognitive diminution and structural encephalon aging almost successful parallel complete time.

"This does not detract from nan truth that starting from a amended cognitive reserve provides an advantage, because if you commencement higher, you will extremity up higher. Clearly, acquisition and early schooling amended cognitive usability passim life, but they do not power nan complaint of diminution aliases nan structural aging of nan brain. Regardless of nan acquisition level, each brains alteration successful very akin ways successful midlife and aged age", Cattaneo continues.

The insubstantial raises important questions for nationalist argumentation connected encephalon wellness and patient aging. "While promoting acquisition remains essential, nan results bespeak that it is not capable for patient aging. That is, it is not capable to accumulate years of schooling to protect nan encephalon from aging. A broader, multifactorial attack is needed that includes lifelong interventions specified arsenic beingness activity, ongoing cognitive stimulation, societal relationships and prevention of vascular consequence factors", concludes Javier Solana, investigation head astatine Institut Guttmann.

Source:

Journal reference:

Fjell, A. M., et al. (2025). Reevaluating nan domiciled of acquisition connected cognitive diminution and encephalon aging successful longitudinal cohorts crossed 33 Western countries. Nature Medicine. doi.org/10.1038/s41591-025-03828-y.

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