Semaglutide May One Day Be Used To Treat Cocaine Addiction

A supplier already prescribed for type 2 glucosuria and obesity whitethorn 1 time beryllium utilized to dainty cocaine addiction. In animal studies, researchers astatine nan University of Gothenburg, Sweden, recovered that semaglutide reduced some cocaine usage and relapse.

One of nan world's astir prescribed narcotics for type 2 glucosuria and obesity, semaglutide besides reduced rats' information to support taking cocaine. Scientists judge nan supplier whitethorn blunt cocaine's expertise to raise dopamine levels successful nan brain, lowering nan consciousness of reward. Exactly really semaglutide useful successful nan encephalon is still not afloat understood.

The study, published successful nan diary European Neuropsychopharmacology, was based connected experiments successful which rats were trained to self-administer cocaine. On average, cocaine usage dropped by 26 percent, relapse-like behaviour by 62 percent, and information to activity nan supplier by 52 percent.

Needs to beryllium tested successful humans

The lead writer is Cajsa Aranäs, a interrogator astatine nan Sahlgrenska Academy, University of Gothenburg:

"Our results show that an established supplier tin impact cardinal behaviors down cocaine addiction. We dream this could unfastened nan measurement for caller treatments, but objective tests are needed earlier we cognize if nan aforesaid effect is seen successful patients."

No approved narcotics today

Elisabet Jerlhag, Professor of Pharmacology astatine nan Sahlgrenska Academy, University of Gothenburg, led nan study:

"There is simply a pressing request for treatments for cocaine addiction. Currently, nary narcotics are available, and nan consequence of relapse is very high. If these findings successful rats clasp up successful objective trials, semaglutide could go nan first pharmacological action to complement psychological therapy and support programs."

Several GLP-1 receptor narcotics are presently approved worldwide, but semaglutide is nan champion known, sold nether names specified arsenic Ozempic and Wegovy.