Reclassifying Wine Intake Reshapes The Mediterranean Diet’s Cognitive Impact

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Scoring vino arsenic a use successful Mediterranean fare devices whitethorn blur important diet–cognition patterns, while reverse scoring reveals humble links pinch amended cognitive screening scores successful older adults astatine precocious consequence of dementia.

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Study: Challenging nan Wine Component successful Mediterranean Diet Scores: Cognitive Outcomes successful Portuguese Adults astatine High Risk of Dementia. Image Credit: doganyavas / Shutterstock

A caller study successful nan journal Nutrients examined really 2 methods of measuring adherence to nan Mediterranean fare power nan nexus betwixt fare adherence and cognitive capacity among older adults successful Portugal.

The 2 methods disagree successful really vino depletion is scored. No important narration was observed erstwhile vino was considered beneficial, but erstwhile vino depletion was reverse-scored, higher adherence was linked pinch amended cognitive performance.

Mediterranean Diet Characteristics and Alcohol Scoring Challenges

The Mediterranean fare is simply a culturally rooted, plant-forward eating shape recognized globally for its wellness benefits. It emphasizes fruits, vegetables, legumes, nuts, full grains, and extra-virgin olive oil, pinch mean intake of fish, achromatic meat, and dairy, and constricted depletion of sweets and reddish aliases processed meats.

Traditionally, mini amounts of vino are consumed pinch meals. As Europe experiences accelerated organization aging, peculiarly successful Portugal, wherever nan aging scale is among nan highest, age-related cognitive diminution has go a awesome nationalist wellness concern.

Evidence Linking Mediterranean Diet and Cognitive Health

Evidence from various world cohorts suggests that greater adherence to nan Mediterranean fare is associated pinch reduced consequence of chronic illness and amended cognitive outcomes, including improved memory, world cognition, and beingness usability successful older adults. However, astir studies do not see Portuguese participants and often trust connected a azygous cognitive test, which limits nan extent of assessment.

A further complication is nan inconsistent scoring of vino depletion successful nan Mediterranean Diet Adherence Screener. While nan original type awards points for mean vino intake, a Portuguese telephone-validated type reverses this scoring. 

These discrepancies are notable because emerging investigation suggests that moreover debased levels of intoxicant whitethorn exert neurotoxic effects. To reside these issues, researchers evaluated really different ways of scoring vino intake whitethorn power associations betwixt nan Mediterranean fare and cognitive usability successful Portuguese older adults astatine elevated dementia risk.

Participant Recruitment and Eligibility Criteria

Researchers utilized cross-sectional information collected betwixt January and May 2023 successful Porto, Portugal. The subordinate group consisted of 75 adults aged 55 to 85 years who had an elevated consequence of dementia, arsenic wished by nan Cardiovascular Risk Factors, Aging, and Dementia score.

Additional eligibility criteria included astatine slightest 4 years of acquisition and a cognitive people supra age- and education-adjusted thresholds. Individuals pinch dementia, awesome disability, participation-limiting conditions, aliases insufficient autonomy successful regular activities were excluded. Ethical support was obtained from nan applicable location authorities.

Cognitive Assessment Tools and Impairment Definitions

Cognitive usability was measured by trained interviewers utilizing 3 validated tools: nan Montreal Cognitive Assessment, nan Addenbrooke Cognitive Examination Revised, and nan Mini-Mental State Examination. Probable cognitive impairment was defined arsenic capacity little than 1.5 modular deviations beneath normative values for property and education.

Mediterranean Diet Scoring Using Original and Reverse Wine Approaches

Mediterranean fare adherence was assessed utilizing nan 14-item Mediterranean Diet Adherence Screener successful 2 scoring formats. The original type awards a constituent for mean vino intake, defined arsenic 7 to 14 glasses per week.

The revised reverse-scored type awards a constituent for drinking little than 1 information of vino daily. Sociodemographic and manner factors were collected utilizing system questionnaires. Group comparisons utilized chi-square, Fisher’s exact, Mann-Whitney, aliases Kruskal-Wallis tests.

Associations betwixt fare scores and cognitive outcomes were examined utilizing study of covariance models adjusted for age, sex, assemblage wide index, education, and beingness activity, pinch cognitive scores log-transformed owed to non-normality.

Participant Characteristics and Lifestyle Profiles

The subordinate group, comprising 75 adults, was predominantly female and had an mean property of 70 years. One-third were overweight and one-fifth were obese. Most had astatine slightest 10 years of education, and complete half reported monthly incomes supra 2 1000 euros.

Few presently smoked aliases engaged successful regular moderate-to-vigorous beingness activity. Using nan original Mediterranean fare scoring, only 17 percent achieved precocious adherence, but this accrued to 33 percent erstwhile vino intake was reverse-scored. Dietary adherence was not importantly associated pinch immoderate sociodemographic aliases manner factor.

Cognitive Outcomes and Sociodemographic Associations

Probable cognitive impairment was detected successful astir 9% of participants utilizing nan Montreal Cognitive Assessment and nan Addenbrooke's Cognitive Examination Revised, but successful much than half of participants utilizing nan Mini-Mental State Examination.

The study suggests that this discrepancy whitethorn bespeak nan higher sensitivity of nan Mini-Mental State Examination to mood-related factors specified arsenic anxiety, which are much communal successful women who represented nan mostly of nan sample.

Higher education, higher income, and non-smoking position were consistently associated pinch amended cognitive performance, whereas property was associated only pinch Addenbrooke Cognitive Examination Revised scores. Sex, assemblage wide index, and beingness activity were not importantly related to cognitive outcomes.

Associations Between Diet Scoring Methods and Cognitive Measures

In adjusted models, original Mediterranean fare scores were not linked pinch capacity connected immoderate cognitive test. The reverse-scored type showed a borderline relation pinch Montreal Cognitive Assessment capacity and a important affirmative relation pinch Mini-Mental State Examination scores.

Among each covariates, acquisition accounted for nan largest proportionality of variance successful cognitive outcomes, contributing betwixt 18% and 35%.

Interpretation of Wine Scoring Effects connected Diet and Cognition

The study recovered nary narration betwixt Mediterranean fare adherence and cognition erstwhile utilizing nan original scoring; however, reversing nan vino point produced a humble relation pinch Mini-Mental State Examination performance, suggesting that nan scoring of intoxicant meaningfully influences nan findings.

The usage of aggregate cognitive measures and observant accommodation for confounders are strengths of this work. However, limitations see a mini sample, reliance connected volunteers, constricted statistical power, a cross-sectional design, and dependence connected screening devices alternatively than afloat neuropsychological batteries. 

Overall, nan results propose that treating vino arsenic beneficial whitethorn obscure important relationships betwixt fare and cognition, highlighting nan request for larger studies to refine dietary appraisal devices for aging research.

Journal reference:

  • Mesquita, A., de Sousa, D., Padrão, P., Costa, A.R., Moreira, P. (2025). Challenging nan Wine Component successful Mediterranean Diet Scores: Cognitive Outcomes successful Portuguese Adults astatine High Risk of Dementia. Nutrients 17(22). DOI: 10.3390/nu17223576, https://www.mdpi.com/2072-6643/17/22/3576
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