Pesticide Exposure During Pregnancy Linked To Higher Death Risk In Children With Leukemia

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Public interest continues to turn astir nan harmful effects of pesticides and different biology pollutants, particularly for children. Pesticides person antecedently been linked to a higher consequence of processing puerility leukemia. Now a caller study shows that children pinch leukemia who were exposed to pesticides during their mother's gestation person a higher consequence of death.

The study, published in Cancers, examined much than 800 children pinch acute lymphoblastic leukemia (ALL) and really pesticide vulnerability affected five-year endurance rates. Children exposed to immoderate pesticide during gestation faced a 60% higher consequence of death, while those exposed to rodenticides, a type of pesticide, during gestation had a 91% accrued risk. Among each children studied, 92% were exposed to astatine slightest 1 type of pesticide earlier aliases aft birth, showing really wide these toxic chemicals are successful homes and environments wherever children live. 

This study highlights that exposures successful nan location environment, moreover earlier a kid is born, whitethorn person lasting effects connected endurance aft a leukemia diagnosis. While much investigation is needed, nan findings underscore nan value of reducing children's vulnerability to harmful pesticides whenever possible."

Lena Winestone, MD, MSHP, pediatric hematologist-oncologist at UCSF Benioff Children's Hospitals and co-author of nan paper 

Exposure cuts crossed race, income lines 

Children diagnosed pinch ALL earlier property one, those from families pinch debased acquisition attainment and income, and Black children had nan highest wide decease rates, while achromatic children exposed to rodenticides showed higher decease rates than different groups. Breastfeeding appeared to person a protective effect wide for children. 

"This investigation is simply a powerful reminder that crab outcomes aren't wished only by aesculapian attraction - they're besides linked to nan biology exposures and conditions successful which families live," said first writer Seema Desai, MD, MPH, astatine nan University of California, Berkeley School of Public Health. 

Environmental pollutants 

The study adds to caller investigation that recovered children exposed to baccy fume and aerial contamination during gestation and aft commencement are besides astatine an accrued consequence of death. Children are particularly susceptible to toxic chemicals, fixed nan higher concentrations comparative to their processing assemblage size.

Although systematic reviews person linked pesticides pinch worsened cognitive, behavioral, and centrifugal outcomes successful children generally, resources to measure and mitigate biology pollutants lag crossed nan country, according to other research. To capable this gap, UCSF's Western States Pediatric Environmental Health Specialty Units (WSPEHSU) offers free resources to trim pesticide vulnerability done its Prescriptions for Prevention. 

Source:

Journal reference:

Desai, S., et al. (2025). Pre- and Postnatal Exposures to Residential Pesticides and Survival of Childhood Acute Lymphoblastic Leukemia. Cancers. doi.org/10.3390/cancers17060978

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