People With Type 1 Diabetes Face Higher Risk Of Developing Dementia

Having type 1 glucosuria is associated pinch a higher consequence of processing dementia, according to a study published March 18, 2026, in Neurology®, nan aesculapian diary of the American Academy of Neurology. Type 2 glucosuria is besides associated pinch a higher consequence of dementia compared pinch not having diabetes. This study shows an relation and does not beryllium that glucosuria causes dementia.

Type 1 glucosuria is rare, accounting for astir 5% of glucosuria cases.

"As advances successful aesculapian attraction person extended nan lives of people pinch type 1 diabetes, it's becoming progressively important to understand nan narration of type 1 glucosuria to nan consequence of dementia," said study writer Jennifer Weuve, MPH, ScD, of Boston University. "We person known that type 2 glucosuria is linked to an accrued consequence of dementia, but this caller investigation suggests that, unfortunately, nan relation whitethorn beryllium moreover stronger for those pinch type 1 diabetes."

The study progressive 283,772 group pinch an mean property of 64. Of those, 5,442 had type 1 glucosuria and 51,511 had type 2 diabetes. The participants were followed for an mean of 2.4 years. During that time, 2,348 group developed dementia, including 144 of nan group pinch type 1 diabetes, aliases 2.6%; 942 of nan people pinch type 2 diabetes, aliases 1.8%; and 1,262 of nan 226,819 group who did not person diabetes, aliases 0.6%.

After accounting for factors, specified arsenic property and acquisition level, nan researchers estimated that group pinch type 1 glucosuria were astir 3 times arsenic apt to create dementia arsenic group without diabetes. People pinch type 2 glucosuria were doubly arsenic apt to create dementia arsenic group without diabetes. Weuve added that successful this study, an estimated 65% of dementia cases among group pinch type 1 glucosuria could beryllium attributed to nan information itself.

"Type 1 glucosuria is not common, truthful this information accounts for a mini fraction of each dementia cases. But for nan increasing number of group pinch type 1 glucosuria who are complete 65 years old, these findings underscore nan urgency of knowing nan ways successful which type 1 glucosuria influences dementia consequence and really we tin forestall aliases hold it," Weuve said.

A limitation of nan study is that glucosuria and dementia were identified utilizing physics wellness records and study data, which whitethorn not seizure each diagnosis.

The study was supported by nan National Institutes of Health.