In patients of reproductive property who person cancer, fertility preservation for imaginable children successful nan early should beryllium a precocious priority. A believe article published successful CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.250519 describes nan successful preservation of ovarian insubstantial successful a young female undergoing urgent chemotherapy and demonstrates a caller exemplary of attraction for Canada.
"This lawsuit illustrates nan analyzable challenges faced by young patients pinch crab who desire biologic children but require urgent curen that threatens their reproductive potential," writes Dr. Jennia Michaeli, a fertility master astatine Mount Sinai Hospital, portion of Sinai Health, and clinician–investigator and adjunct professor astatine the University of Toronto, Toronto, Ontario, pinch coauthors.
Unfortunately, galore life-saving interventions - including reproductive organ surgery, chemotherapy, and abdominopelvic radiation - increase nan consequence of infertility and reproductive endocrine dysfunction."
Dr. Jennia Michaeli, Fertility Specialist, Mount Sinai Hospital
The patient, located 380 km from Toronto, decided to acquisition ovarian insubstantial preservation aft being counselled connected options, nan risks of surgery, and steps successful nan procedure. The fertility squad astatine Mount Sinai successful Toronto coordinated attraction remotely pinch nan patient's section oncologist and gynecologist to guarantee nan insubstantial was removed surgically, past transported nether continuous somesthesia power to a specialized embryology laboratory astatine Mount Sinai.
Despite Canadian guidelines endorsing fertility preservation arsenic a modular of attraction for patients pinch cancer, diligent distress astir survival, a deficiency of expert knowledge of options, and constricted capacity successful nan strategy airs barriers to wider take of nan practice.
This patient's lawsuit shows that implementing a centralized "hub-and-spoke" exemplary could thief unfastened nan doors to ovarian insubstantial cryopreservation for young patients pinch crab crossed Canada.
"We successfully delivered specialized oncofertility services done coordinated attraction pathways that flooded geographical barriers, which serves arsenic a impervious of concept," constitute nan authors.
"The described exemplary intends to trim infertility and reproductive endocrine dysfunction, minimize nan psychosocial effect of infertility, and heighten nan value of life for patients and their families by improving entree and coordination of care."
Source:
Journal reference:
Michaeli, J., et al. (2025). Fertility preservation by ovarian insubstantial proscription and centralized cryobanking for a 20-year-old female pinch Hodgkin lymphoma. Canadian Medical Association Journal. DOI:10.1503/cmaj.250519. https://www.cmaj.ca/content/197/39/E1307.
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