The Society of Nuclear Medicine and Molecular Imaging (SNMMI), American Society of Nuclear Cardiology (ASNC), European Association of Nuclear Medicine (EANM), and American College of Nuclear Medicine (ACNM) person issued a caller objective line for 18F-flurpiridaz PET myocardial perfusion imaging (MPI) and humor travel quantitation. The guideline, co-published successful The Journal of Nuclear Medicine and nan Journal of Nuclear Cardiology, is intended to assistance atomic cardiology practitioners successful nan optimal exertion of 18F-flurpiridaz PET for MPI, including recommendations for diligent selection, imaging protocols, and mentation of results.
Coronary artery illness (CAD) is nan starring origin of decease worldwide and is responsible for nan hospitalization, functional decline, and reduced value of life for millions of patients each year. Early and meticulous test and consequence stratification of CAD are basal for guiding curen and improving diligent outcomes. MPI is simply a cornerstone of non-invasive appraisal of myocardial ischemia.
MPI tin beryllium performed pinch SPECT aliases PET. 18F-flurpiridaz is simply a caller PET radiotracer that has demonstrated favorable imaging and physiological properties compared to accepted SPECT agents. Clinical studies person shown that it provides superior image quality, improved diagnostic accuracy, and greater sensitivity successful detecting clinically important coronary artery stenosis compared pinch accepted SPECT agents. It is peculiarly valuable successful patients for whom SPECT whitethorn beryllium little effective, specified arsenic those pinch obesity aliases mini near ventricles.
Multiple shape II and 2 shape III objective tests person further established nan inferior of 18F-flurpiridaz arsenic a valuable PET radiotracer for nan non-invasive information of CAD. Owing to its favorable molecular imaging characteristics and extended half-life, 18F-flurpiridaz is poised to go a valuable supplier for cardiac accent PET imaging, offering clinicians a robust instrumentality for nan information of CAD."
René R. Sevag Packard, MD, PhD
The line includes accusation connected objective indications, contraindications, and considerations for 18F-flurpiridaz PET. It addresses qualifications and responsibilities of unit performing cardiac accent testing utilizing 18F-flurpiridaz, protocol (and imaginable protocol modifications), biodistribution and dosimetry, and nan 18F-flurpiridaz PET workflow. Technologist considerations are besides included.
"This archive is designed to beforehand high-quality, safe, and effective atomic medicine believe successful nan information of CAD," emphasized nan authors. "Our dream is that nan line enhances objective decision-making, standardizes objective practice, improves diagnostic accuracy, and optimizes assets utilization to guarantee information and amended diligent outcomes."
SNMMI, ASNC, EANM, and ACNM periodically specify caller process standards/practice guidelines for atomic medicine believe to thief beforehand nan subject of atomic medicine and to present effective and safe aesculapian attraction to patients. Each standard/guideline, representing a argumentation connection by these groups, undergoes a thorough statement process successful which it is subjected to extended review.
Source:
Journal reference:
Sevag Packard, R. R., et al. (2025) SNMMI/EANM/ASNC/ACNM Procedure Standard/Practice Guideline for 18F-Flurpiridaz PET Myocardial Perfusion Imaging and Blood Flow Quantitation. Journal of Nuclear Medicine. doi.org/10.2967/jnumed.125.270873.
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