Gut Bacteria Metabolize Nitrogen Compounds To Prevent Cancer-causing Nitrosamines

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Nitrogen metabolism of gut germs tin supply wellness benefits. Specifically, gut microbes metabolize dietary nitrates and nitrites and forestall nan statement of cancer-causing compounds called nitrosamines. New investigation published successful The FEBS Journal sheds ray connected these processes and pinpoints which types of germs are astir important.

Investigators recovered that Escherichia coli-and to a lesser extent, type of nan genera Lactobacillus, Bacteroides and Phocaeicola-can efficiently metabolize different forms of nitrogen, frankincense preventing carcinogenic nitrosamine formation. They besides demonstrated that this bacterial processing is captious to alteration microorganisms to past and colonize nan intestinal tract, apt preventing harmful changes successful nan creation of nan gut microbiota.

The findings item nan value of nan gut microbiota successful preventing nan statement of harmful nitrogen metabolites, perchance decreasing nan consequence of definite cancers. The study besides illustrates really nan microbiota facilitates crosstalk betwixt our fare and nan gut, frankincense having important implications for some wellness and disease.

The find that circumstantial gut germs quickly metabolize nitrite suggests a protective system done which nan microbiota contributes to nan attraction of intestinal and systemic health."

Prof. Uwe Deppenmeier, corresponding author, University of Bonn, Germany

Source:

Journal reference:

Hager, N., et al. (2025). Distribution and activity of nitrate and nitrite reductases successful nan microbiota of nan quality intestinal tract. The FEBS Journal. doi.org/10.1111/febs.70299

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