Global Vaccination Effort Saved 2.5 Million Lives From Sars-cov-2

Thanks to vaccinations against SARS-CoV-2 successful nan play 2020-2024 2.533 cardinal deaths were prevented astatine world level, 1 decease was avoided for each 5,400 doses of vaccine administered. The 82% of nan lives saved by vaccines progressive group vaccinated earlier encountering nan virus, 57% during nan Omicron period, and 90% progressive group aged 60 years and older. In all, vaccines person saved 14.8 cardinal years of life (one twelvemonth of life saved for 900 doses of vaccine administered).

These are immoderate of nan information released successful an unprecedented study published successful nan diary Jama Health Forum and coordinated by Prof. Stefania Boccia, Stefania Boccia, Professor of General and Applied Hygiene astatine Università Cattolica, pinch contributions from Dr. Angelo Maria Pezzullo, Researcher successful General and Applied Hygiene, and Dr. Antonio Cristiano, a aesculapian resident successful Hygiene and Preventive Medicine.

The 2 researchers spent a play astatine Stanford University, collaborating straight pinch nan group of Professor John P.A. Ioannidis, head of nan Meta-Research Innovation Center (METRICS), successful nan discourse of nan task "European web unit eXchange for integrAting precision wellness successful nan wellness Care sysTems- ExACT" funded by nan European Research Excellence Programme RISE project-Marie Slodowska Curie and coordinated by Professor Stefania Boccia.

Professor Boccia and Dr. Pezzullo explain: "Before ours, respective studies tried to estimate lives saved by vaccines pinch different models and successful different periods aliases parts of nan world, but this 1 is nan astir broad because it is based connected worldwide data, it besides covers nan Omicron period, it besides calculates nan number of years of life that was saved, and it is based connected less assumptions astir nan pandemic trend."

The study

The experts studied worldwide organization data, applying a bid of statistical methods to fig retired who among nan group who became sick pinch COVID did either earlier aliases aft getting vaccinated, earlier aliases aft Omicron period, and really galore of them died (and astatine what age).

"We compared this information pinch nan estimated information modeled successful nan absence of COVID vaccination and were past capable to cipher nan numbers of group who were saved by COVID vaccines and nan years of life gained arsenic a consequence of them."

Dr. Angelo Maria Pezzullo, Researcher, General and Applied Hygiene, Universita Cattolica del Sacro Cuore

It besides turned retired that astir of nan saved years of life (76%) progressive group complete 60 years of age, but residents successful semipermanent attraction accommodation contributed only pinch 2% of nan full number. Children and adolescents (0.01% of lives saved and 0.1% of life years saved) and young adults aged 20-29 (0.07% of lives saved and 0.3% of life years saved) contributed very small to nan full benefit.

Professor Boccia concludes: 'These estimates are substantially much blimpish than erstwhile calculations that focused chiefly connected nan first twelvemonth of vaccination, but intelligibly show an important wide use from COVID-19 vaccination complete nan play 2020-2024. Most of nan benefits, successful position of lives and life-years saved, person been secured for a information of nan world organization who are typically much fragile, nan elderly'.