From fare and surface science to transportation mode and preterm birth, observe really a mother’s travel shapes nan unsocial nutritional floor plan of her bosom milk, perchance influencing lifelong health.
Diagram of factors that whitethorn impact macronutrient and power contented of bosom milk. Abbreviation: IUGR, intrauterine maturation restriction. Factors That May Affect Breast Milk Macronutrient and Energy Content: A Critical Review
In a caller study published successful nan diary Nutrients, researchers successful Portugal reviewed nan factors affecting power and macronutrient contented of bosom milk.
Breast beverage creation whitethorn accommodate to maternal factors, neonatal characteristics, and obstetrical factors. The effect of changes successful bosom beverage creation connected offspring maturation and wellness remains unknown. In nan coming study, researchers reviewed nan factors affecting nan power and macronutrient contented of bosom milk. They searched aesculapian lit databases utilizing applicable position and identified 35 studies for a broad reappraisal utilizing Levels of Evidence (LOE) classification and focusing connected studies published aft 2006 for methodological consistency. The factors affecting macronutrient and power contented of bosom beverage were stratified arsenic maternal, obstetrical, and neonatal.
Maternal factors affecting bosom beverage power and macronutrient contented were maternal age, socioeconomic status, geographical location, dietary intake, nutritional status, and lactation stage. A study observed that beverage from mothers pinch a little socioeconomic position was richer successful monounsaturated and n-9 fatty acids, while beverage from mothers pinch a higher socioeconomic position was richer successful polyunsaturated, n-3, and n-6 fatty acids (PUFAs). Milk from self-employed mothers aliases those moving successful nan backstage assemblage was recovered to person a higher fat and macromolecule contented than that from unemployed mothers aliases those moving successful nan nationalist sector. Older maternal property has been reported to correlate pinch much fat successful colostrum, transitional, and mature milk.
A study recovered accordant grounds that bosom beverage fatty acerb contented varies by geographical location, apt owed to dietary differences. For instance, Swedish mothers’ bosom beverage was recovered to person higher eicosapentaenoic acerb (EPA) and docosahexaenoic acerb (DHA; n-3) but little linoleic acerb (n-6) contented than Chinese mothers’ bosom milk. Maternal obesity has been associated pinch elevated fat contented successful bosom milk, though transitional beverage whitethorn show little fat, pinch grounds for higher lactose being little accordant and chiefly observed successful colostrum.
A systematic reappraisal recovered that higher maternal assemblage fat was associated pinch accrued fat contented successful bosom milk. Lower maternal fat intake has been associated pinch higher eicosapentaenoic acerb and docosahexaenoic acerb contented successful bosom milk. Higher maternal macromolecule intake has been linked to accrued energy, carbohydrate, fat, and macromolecule content. Higher maternal intake of PUFAs has been recovered to correlate pinch higher PUFA contented successful bosom milk.
Different lactation stages power bosom beverage macronutrient content. A cross-sectional study recovered little macromolecule and higher fat contented successful mature beverage than successful transitional milk. A meta-analysis of preterm beverage reported that during nan first 12 weeks postpartum, location is simply a progressive summation successful fat contented and a progressive diminution successful macromolecule content, pinch carbohydrate and power contented expanding initially earlier achieving a dependable state. This shape is astir accordant for preterm milk, while word beverage shows variations (for example, power whitethorn summation continuously).
Obstetrical factors that whitethorn effect nan power and macronutrient contented of bosom beverage see parity, preterm delivery, mode of delivery, and gestation morbidities (gestational glucosuria and hypertensive disorders). Studies person suggested associations betwixt nan parity number and nan macronutrient contented of bosom milk. Fat contented is reported to summation pinch parity number up to three, beyond which nan inclination whitethorn reverse.
The grade of prematurity whitethorn effect bosom milk's power and macronutrient content. A study recovered higher existent macromolecule and full power contented successful bosom beverage pinch expanding prematurity. Another study recovered higher power and fat but typically little carbohydrate contented successful beverage from mothers pinch preterm transportation than successful beverage from those who gave commencement astatine term. Breast beverage creation could besides alteration by nan mode of delivery.
Milk from mothers who underwent cesarean conception had elevated fat content, while beverage from those pinch vaginal transportation had accrued carbohydrate content. A systematic reappraisal recovered that mature beverage and colostrum from hypertensive mothers had higher macromolecule contented compared to normotensive mothers. Hypertensive disorders were besides linked to higher power contented (chronic hypertension) and little DHA (preeclampsia), whereas gestational hypertension was associated pinch little beverage power and fat.
A different study reported higher existent macromolecule and full power contented successful beverage from mothers pinch chronic hypertension. On nan different hand, mature beverage from mothers pinch gestational glucosuria was recovered to person a little power and fat contented compared to euglycemic mothers. A systematic reappraisal reported little lactose and fat contented successful beverage from mothers pinch glucosuria mellitus.
Neonatal factors that impact bosom milk’s power and macronutrient contented see intersexual dimorphism and anthropometrics. Multiple studies conflict connected intersexual dimorphism: immoderate study higher power and fat contented successful beverage for males, while others show nan other for females. Lower carbohydrate contented successful beverage for males is much consistently observed. Higher commencement magnitude was independently correlated pinch higher power and fat contented successful bosom milk.
In sum, various obstetrical, maternal, and neonatal factors impact nan power and macronutrient contented of bosom milk. Milk from obese and overweight mothers has been reported to beryllium fat- and energy-rich, though transitional beverage whitethorn differ. Increased power and macromolecule contented person been reported successful beverage from mothers pinch earlier preterm delivery, particularly highly preterm births. Higher macromolecule and power contented and adaptable fat changes were reported successful beverage from mothers pinch hypertensive disorders, while little fat characterized beverage from diabetic mothers. Though intersexual dimorphism findings conflict, antheral babe activity whitethorn beryllium associated pinch little beverage carbohydrate. The reappraisal acknowledges limitations, including heterogeneity successful study designs and methodology.
Journal reference:
- Rocha-Pinto I, Pereira-da-Silva L, Silva DE, Cardoso M (2025). Factors That May Affect Breast Milk Macronutrient and Energy Content: A Critical Review. Nutrients, 17(15). DOI: 10.3390/nu17152503, https://www.mdpi.com/2072-6643/17/15/2503
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