Abselion Launches Aavx And Aav9 Total Capsid Quantification Kits

Abselion, a pioneering life sciences exertion institution focused connected simplifying biomolecule quantification, has expanded its merchandise offering, pinch nan motorboat of nan AAVX Total Capsid Quantification Kit and nan AAV9 Total Capsid Quantification Kit. Both kits are designed for usage pinch its Amperia™ benchtop quantification level and see Thermo Fisher Scientific's CaptureSelect™ affinity reagents. Combining these trusted reagents pinch Abselion's accordant assay format reduces nan request for in-house optimization. These kits connection researchers moving successful adeno-associated microorganism (AAV) improvement and characterization a much streamlined and accessible workflow to make reproducible titer measurements crossed a wide scope of serotypes and process conditions.

Abselion's Amperia benchtop level is simply a simple-to-use solution for accelerated and meticulous automated quantification of a scope of biomolecules, without optics, fluidics, aliases master training. Each kit is supplied successful a ready-to-use format, including sensor strips, assay plates, matched discovery reagents, and assay buffers for nan binding and discovery steps. The expanded kit scope enhances nan inferior of Amperia for scientists moving crossed gene therapy improvement and process workflows, offering a practical, dependable attack to full capsid quantification from purified aliases analyzable samples.

Abselion has entered into a licensing statement pinch Thermo Fisher Scientific to incorporated CaptureSelect affinity reagents into its AAV quantification kits. CaptureSelect exertion is based connected recombinant single-domain antibodies designed for precocious target specificity, debased cross-reactivity, and accordant batch capacity to guarantee robust titer quantification. With nan integration of these reagents, nan caller kits beforehand Abselion's AAV assay format, bringing improved capacity and broader serotype applicability.

Both kits usage a sandwich-style immunoassay format, successful which biotin- and HRP-conjugated CaptureSelect antibodies are sequentially applied to hindrance AAV capsids. The resulting awesome is detected electrochemically utilizing Amperia sensor strips, enabling meticulous quantitative discovery crossed a scope of AAV sample types and concentrations.

The AAVX Total Capsid Quantification Kit includes CaptureSelect Anti-AAVX Biotin and HRP Conjugates, enabling wide serotype sum including AAV1-8 and AAVrh10. The AAV9 Total Capsid Quantification Kit incorporates CaptureSelect Anti-AAV9 Biotin and HRP Conjugates for focused quantification of AAV9 particles.

Reliable quantification of full AAV capsid attraction is cardinal to maintaining consistency and supporting informed decision-making. The integration of Thermo Fisher Scientific's CaptureSelect reagents strengthens nan capacity of Abselion's AAV kits and reflects our attraction connected making high-quality titer measurement simpler and much accessible. With these additions, Amperia offers researchers a ready-to-use solution that combines trusted reagent technologies pinch a streamlined assay format, enabling reliable quantification crossed a wider scope of serotypes and improvement workflows."

Dr Ruizhi Wang, CEO and Founder, Abselion

Dr Kelly Flook, Sr. Manager, Product Management, Pharma Analytics, Thermo Fisher Scientific, said: "CaptureSelect affinity reagents are designed to present precocious specificity and lot-to-lot consistency, making them good suited for applications specified arsenic AAV capsid quantification. We're pleased that Abselion has incorporated these reagents nether licence to support their assay kits for nan Amperia platform."