Hiiragi Group And Prevedel Group Collaborate With Prospective Instruments To Pioneer Intravital Multiphoton Microscopy For Early Embryo Research

Prof. Takashi Hiiragi (Hubrecht Institute), Dr. Robert Prevedel (European Molecular Biology Laboratory), and Dr. Lukas Krainer (Prospective Instruments) person launched an interdisciplinary collaboration to create a caller intravital microscopy level for studying mammalian embryo implantation.

Prof. Takashi Hiiragi explains: "Our investigation explores really self-organisation drives nan emergence of forms and patterns successful early mammalian embryos. By combining genetics, microscopy, biophysics, engineering, and modelling, we analyse really a seemingly elemental cluster of cells develops into organised structures."

Prof. Takashi Hiiragi continues: "To study embryo improvement successful nan uterus,  we established a caller interdisciplinary collaboration with the Prevedel group astatine EMBL Heidelberg and the manufacture partner Prospective Instruments to build nan intravital microscope. We person extensively tested each microscope constituent to place and observe nan embryo-uterus interaction, and optimized and finalized its design. The mammalian implantation process is mostly enigmatic, and nan move embryo-uterus relationship and its underlying mechanisms are poorly understood. This caller intravital microscope will supply a caller model and perchance toggle shape nan investigation of early mammalian development. Fortunately, Prospective Instruments could supply nan level of customizable creation we needed to alteration our imaging research."

We are excited to participate successful a task that genuinely pushes nan limits of multiphoton imaging by combining specified divers imaging modalities. For galore years, we person been supporting researchers pinch our state-of-the-art multiphoton microscopy solutions. Now, by integrating high-resolution spectral domain optical coherence tomography (OCT) successful an automated and user-friendly system, we alteration researchers to summation insights from their samples that were not imaginable before."

Dr. Lukas Krainer